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KMID : 1009020190170030443
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Clinical Psychopharmacology and Neuroscience
2019 Volume.17 No. 3 p.443 ~ p.445
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New Onset Obsessive Compulsive Disorder Following High Frequency Repetitive Transcranial Magnetic Stimulation over Left Dorsolateral Prefrontal Cortex for Treatment of Negative Symptoms in a Patient with Schizophrenia
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Garg Harshit
Kumar Saurabh
Singh Swarndeep
Kumar Nand
Verma Rohit
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Abstract
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Obsessive-compulsive symptoms and/or obsessive-compulsive disorders (OCD) are frequently comorbid with schizophrenia, though the exact clinical and etiological relationship between them is poorly understood. Here we describe a case that, to the best of our knowledge, is the first report of new-onset OCD in a patient who was receiving high-frequency repetitive transcranial magnetic stimulation over left dorsolateral pre-frontal cortex as an adjuvant therapy for negative symptoms of schizophrenia. Thisreport supports our understanding of OCD as a brain disorder involving hyperactivity of pre-frontal cortex and cortico-striatal-thalamo-cortical circuit dysfunction.
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KEYWORD
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Obsessive-compulsive disorder, Negative symptoms, Schizophrenia, Transcranial magnetic stimulation
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